How are genetic and Infertility linked?
The question often asked by intended parents at fertility clinics worldwide is, “Is infertility genetic?” Discovering infertility can be disheartening, and at Hiremath Hospital PCMC, Pune our dedicated doctors are ready to assist you on your fertility journey. Let’s delve into the genetic aspects of infertility, considering disorders that can impact both female and male fertility.
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Genetic Factors responsible for Male and Female infertility:
Infertility in couples can be linked to genetic factors, ranging from inherited chromosomal abnormalities to gene mutations. These include deletions (missing chromosome pieces), inversions (upside-down chromosomes), mutations (changes in gene DNA sequences), aneuploidy (too many or too few chromosomes), and translocations (misplaced chromosome pieces).
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Genetic Disorders and Female Infertility:
Certain chromosomal abnormalities or gene mutations can affect female fertility, influencing ovulation. Examples include mutations in the cystic fibrosis gene, leading to issues like thicker cervical mucus or ovulation problems, Kallmann syndrome affecting hormone production, and primary ciliary dyskinesia causing infertility due to abnormal cilia in the fallopian tubes.
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Genetic Disorders and Male Infertility:
Chromosomal abnormalities or gene mutations can impact male fertility by affecting sperm production or flow. Examples include mutations in the cystic fibrosis gene causing the absence of the vas deferens, Klinefelter syndrome affecting sperm and testosterone production, and Y chromosome deletion resulting in an abnormal sperm count.
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Comprehensive Evaluation of Infertility:
Infertility is seldom solely attributed to genetic factors; multiple causes are typically involved. Identifying and addressing these factors enhances the effectiveness of infertility treatment. Advances in infertility treatment, including genetic considerations, contribute to increased success rates.
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Some of the uses for PGD/PGS/PGT-A testing include:
Before embarking on IVF or other fertility treatments, our doctors recommend genetic blood tests. Preimplantation genetic diagnosis (PGD/PGS/PGT-A) can prevent the passage of genetic disorders when combined with IVF. This testing aids in discovering inherited health conditions, understanding genetic factors affecting conception, mitigating the risk of passing genetic disorders to children, and even selecting the embryo’s sex during IVF.
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know More about Whether Infertility Is Hereditary:
If you want to know more about the genetic factor that effect infertility, then you can schedule a consultation with our highly esteemed doctors for infertility treatment at Hiremath Hospital PCMC, Reach out to us. Our Doctors are specialized in Obstetrics, Gynecology, Infertility, and Endocrinology. They will help guide you on your fertility path. Learn more, stay updated, and for infertility treatment at PCMC, Pune, you can either visit the hospital or call us at +91-9850460850.
